1.What is Vitamin B1 Hcl?

Thiamine Hydrochloride is vitamin B1. Thiamine hydrochloride is the hydrochloride salt of thiamine, also known as thiamine hydrochloride. It is a water-soluble vitamin purified by humans, primarily existing in the form of vitamin B1.

Thiamine hydrochloride is found in rice bran, germ, yeast, eggs, green leaves, and legumes. As a water-soluble vitamin B1, it can help treat diseases caused by vitamin B1 deficiency. It serves as a nutritional supplement that participates in carbohydrate metabolism within the body and plays a vital role in maintaining normal nerve conduction, as well as the proper functioning of the heart and digestive system.

 

2.How it Works?

In the body, it primarily participates in carbohydrate metabolism, acting as a coenzyme in the catalytic reactions of various enzymes. Specifically, thiamine hydrochloride is involved in the oxidative decarboxylation of pyruvate and α-ketoglutarate during glucose metabolism, generating energy for cellular use. Additionally, it plays an important role in maintaining normal nervous system function, particularly in supporting peripheral nerve conduction.

 

3.Benefits and Use

I. Physiological Functions and Mechanism of Action
Energy Metabolism Regulation
Vitamin B₁ exists in the form of thiamine pyrophosphate (TPP), serving as a coenzyme in key reactions of carbohydrate metabolism (e.g., pyruvate decarboxylation), facilitating the conversion of food into energy (ATP).

Nervous System Support
Maintains the integrity of nerve cell membranes and promotes acetylcholine synthesis, ensuring normal neural signal transmission. Deficiency may lead to peripheral neuritis or cerebral dysfunction.

Cardiovascular Protection
Participates in myocardial energy supply. Deficiency can cause cardiac enlargement, edema, and other manifestations of beriberi heart disease.

II. Deficiency Syndromes and Clinical Manifestations
Dry Beriberi
Primarily characterized by peripheral neuritis, presenting as limb numbness, muscle weakness, and diminished tendon reflexes.

Wet Beriberi
Involves the cardiovascular system, manifesting as palpitations, shortness of breath, and edema, potentially progressing to heart failure in severe cases.

Cerebral Beriberi (Wernicke-Korsakoff Syndrome)
Most commonly observed in chronic alcoholics, symptoms include nystagmus, ataxia, and mental confusion.

III. Primary Clinical Applications
Treatment of Vitamin B₁ Deficiency
Administered orally or via injection to correct deficiency caused by inadequate intake (e.g., long-term polished rice diets), malabsorption (chronic diarrhea), or increased demand (pregnancy, hyperthyroidism).

Adjuvant Therapy for Metabolic Disorders
Used for nutritional support in diabetic peripheral neuropathy, chronic dyspepsia, or patients with hypermetabolic conditions.

Intervention for Alcohol Dependence
Alcohol inhibits B₁ absorption; chronic alcoholics require additional supplementation to prevent brain damage.

 

4.Q&A

Q:Does the company accept sample orders?

A:Yes, our company accepts sample orders.

Q:What is the minimum order quantity for the company?

A:We do not have a minimum order quantity requirement, we arrange according to the customer's needs.

Q:How to ensure the quality of goods?

A:We have a strict QC/QA management system and strict release procedures, and we will provide all procedures to customers before shipment according to their requirements.

Q:Can we see the product quality before the order is shipped?

A:Of course, we always provide a relative Batach (s) 'COA before shipping.

Q:How will you deliver the goods?

A:We will communicate with customers, adopt their suggestions, arrange the most suitable delivery method, and ensure mutual satisfaction.