Nicotinamide Mononucleotide (NMN) is a derivative of vitamin B3 that converts into the coenzyme NAD+ in the body. NAD+ participates in cellular energy metabolism, DNA repair, and aging regulation. Current research focuses on its potential anti-aging effects, though human efficacy and safety require further evidence.
1.What is Nicotinamide Mononucleotide?
Nicotinamide Mononucleotide (NMN) is a derivative of vitamin B3 that converts into the coenzyme NAD+ in the body. NAD+ participates in cellular energy metabolism, DNA repair, and aging regulation. Current research focuses on its potential anti-aging effects, though human efficacy and safety require further evidence.
2.How it Works?
1. NAD+ Precursor
NMN exerts its effects by converting into NAD+ (nicotinamide adenine dinucleotide), a critical coenzyme for:
Cellular energy metabolism (e.g., TCA cycle)
DNA repair
Gene expression regulation
Age-related decline in NAD+ levels may contribute to aging-associated diseases.
2. Potential Physiological Functions
Anti-aging: Animal studies show NMN supplementation improves mitochondrial function, reduces oxidative stress, and extends lifespan in mice.
Metabolic regulation: May enhance glucose/lipid metabolism and alleviate insulin resistance.
Neuroprotection: Improves cognitive function in Alzheimer’s disease model animals.
3.Benefits and Uses
1. Enhancing Cellular Vitality
Nicotinamide mononucleotide (NMN) boosts intracellular energy metabolism, enhances cellular vitality, and maintains cellular health.
2. Improving Metabolism
It helps regulate metabolic processes in the body, promoting the synthesis and breakdown of nutrients to improve metabolic efficiency.
3. Promoting DNA Repair
NMN exhibits certain DNA damage repair capabilities, contributing to the maintenance of genetic stability.
4. Delaying Aging
By influencing cell senescence-related signaling pathways, NMN helps slow down the cellular aging process.
5. Enhancing Cognitive Function
Research suggests that NMN may have a positive impact on improving cognitive function and memory.
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