1.What is L-Ergothioneine?

L-Ergothioneine is a natural antioxidant found in mushrooms, grains (e.g., rye, oats), and certain animal tissues. It exhibits antioxidant, anti-inflammatory, and cytoprotective properties. Since the human body cannot synthesize it autonomously, dietary intake or supplementation is required. Its potential health benefits are currently under extensive research.

Characteristics & Sources

• A sulfur-containing amino acid derivative biosynthesized by microorganisms (e.g., fungi, bacteria) and transferred through the food chain.

• Primary natural sources:

  • Mushrooms (especially porcini, oyster mushrooms, shiitake)

  • Minor amounts in rye, oats, animal liver, and blood.

 

2.How it Works?

Antioxidant Effects
L-Ergothioneine directly scavenges free radicals (e.g., hydroxyl radicals, singlet oxygen), protecting cellular membranes, mitochondria, and other structures from oxidative damage. Its antioxidant capacity is considered superior to glutathione, with prolonged retention in the body.

Anti-inflammatory and Cytoprotective Effects

• Inhibits the NF-κB pathway to reduce inflammatory cytokine release.

• Activates the Nrf2 pathway to enhance cellular antioxidant defense systems.

• Protects neurons, skin cells, and other tissues from chronic diseases or environmental stress.

Metal Ion Chelation
Binds copper, iron, and other metal ions, mitigating oxidative stress induced by metal ion overload.

 

3.Benefits and Uses

1. Health & Anti-Aging
Research indicates L-Ergothioneine may:

• Delay skin photoaging

• Enhance cognitive function

• Offer potential neuroprotective effects against Alzheimer's and Parkinson's diseases

2. Food & Supplements
Approved in some countries as:

• A food additive or dietary supplement to boost antioxidant capacity

• An ingredient in functional foods

3. Medical Research
Under investigation for:

• Adjuvant cancer therapy

• Managing metabolic syndromes (e.g., diabetes)
  Current status: Laboratory/clinical trial phases

 

4.Q&A

Q:Does the company accept sample orders?

A:Yes, our company accepts sample orders.

Q:What is the minimum order quantity for the company?

A:We do not have a minimum order quantity requirement, we arrange according to the customer's needs.

Q:How to ensure the quality of goods?

A:We have a strict QC/QA management system and strict release procedures, and we will provide all procedures to customers before shipment according to their requirements.

Q:Can we see the product quality before the order is shipped?

A:Of course, we always provide a relative Batach (s) 'COA before shipping.

Q:How will you deliver the goods?

A:We will communicate with customers, adopt their suggestions, arrange the most suitable delivery method, and ensure mutual satisfaction.