Grape Seed Extract (GSE), also known as proanthocyanidin, is a natural bioactive substance derived primarily from grape seeds, with oligomeric proanthocyanidins (OPCs) as its core component.
1.What is Grape seed OPC?
Grape Seed Extract (GSE), also known as proanthocyanidin, is a natural bioactive substance derived primarily from grape seeds, with oligomeric proanthocyanidins (OPCs) as its core component. As a potent antioxidant, its free radical scavenging capacity significantly exceeds that of vitamin C and vitamin E. It works by inhibiting lipid peroxidation to repair oxidative damage and modulating glutathione-related enzyme activity.
This extract exhibits antioxidant, anti-inflammatory, and cardiovascular protective properties, including:
Strengthening blood vessel walls
Reducing risks of diabetes and cancer
For skin health, it:
Promotes optimal collagen cross-linking
Mitigates UV-induced damage
Delays wrinkle formation
Experimental studies demonstrate its ability to:
Inhibit cataract progression
Alleviate allergic reactions and inflammatory conditions like arthritis
Reduce oxidative DNA damage in lymphocytes
Widely used as a dietary supplement, GSE has applications in pharmaceuticals, nutraceuticals, and cosmetics.
2.How it Works?
Grape Seed OPC can provide the hydrogen (H) required to quench various reactive oxygen species (ROS). They exhibit significant scavenging effects on hydroxyl radicals (·OH) and other free radicals that cause structural and functional damage to biomembranes through peroxidation, thereby protecting biological organs.
3.Benefits and Use
Grape Seed Proanthocyanidins (Grape seed OPCs) demonstrate multiple biological effects including antioxidant activity, cardiovascular protection, skin health improvement, anti-inflammatory action, and neurological support. By scavenging free radicals, enhancing vascular elasticity, and inhibiting inflammatory factors, it helps maintain physiological balance, particularly in delaying oxidative damage-related diseases.
Grape seed OPCs are potent natural antioxidants, with capacities 20× stronger than vitamin C and 50× stronger than vitamin E. They:
Neutralize free radicals
Reduce oxidative damage to cells, DNA, and proteins
Delay age-related functional decline
Long-term supplementation may lower risks of chronic age-associated diseases.
Mechanisms include:
Enhancing vascular elasticity: Promotes collagen synthesis, maintains vascular integrity, and improves microcirculation.
Regulating lipids: Inhibits LDL oxidation, reducing atherosclerotic plaque formation.
Improving blood flow: Suppresses platelet hyperaggregation, lowering thrombosis risk.
Endogenous protection: Reduces UV-induced free radical damage and melanin production, delaying photoaging.
Reparative effects: Stabilizes collagen/elastin, improving skin elasticity, hydration, and reducing fine wrinkles.
Grape seed OPCs:
Inhibit NF-κB signaling
Reduce pro-inflammatory cytokines (e.g., IL-6, TNF-α)
May aid arthritis, allergies, and gut inflammation.
Crosses the blood-brain barrier
Reduces brain oxidative damage
Inhibits β-amyloid deposition
Potential benefits for cognitive function and neurodegenerative diseases (e.g., Alzheimer’s).
Ocular health: Improves retinal microcirculation, alleviates eye strain.
Anti-allergy: Stabilizes mast cells, reduces histamine release.
Glycemic control: Enhances insulin sensitivity, inhibits AGEs formation.
Q:Does the company accept sample orders?
A:Yes, our company accepts sample orders.
Q:What is the minimum order quantity for the company?
A:We do not have a minimum order quantity requirement, we arrange according to the customer's needs.
Q:How to ensure the quality of goods?
A:We have a strict QC/QA management system and strict release procedures, and we will provide all procedures to customers before shipment according to their requirements.
Q:Can we see the product quality before the order is shipped?
A:Of course, we always provide a relative Batach (s) 'COA before shipping.
Q:How will you deliver the goods?
A:We will communicate with customers, adopt their suggestions, arrange the most suitable delivery method, and ensure mutual satisfaction.
Arshine Lifescience Inc.,
Your Trusted Ingredient Partner.
Add.: Ontario, California, USA
Email: info@arshineusa.com
WhatsApp: +1 6576561513